Safety and Effectiveness
Scientific Validation and Clinical Evidence
Explore the scientific foundation behind PRP and its applications in aesthetic medicine.
Angel® PRP System
Customized PRP Concentration at the Touch of a Button
What Is the Angel System?
The Angel system is a customizable platelet-rich plasma (PRP) preparation system that supports the increasing demand for regenerative therapies in aesthetic medicine. It enables the sterile, automated separation of whole blood into tailored PRP formulations, with adjustable platelet and leukocyte concentrations to meet individual treatment needs.
With the ability to process up to 180 mL of blood and deliver platelet concentrations up to 18× over baseline, the Angel system also allows for precise control over leukocyte levels—including leukocyte-poor PRP for sensitive applications and leukocyte-rich PRP for enhanced regenerative effects. Its neutrophil-low PRP setting helps minimize inflammation, while the proprietary 3-sensor technology and closed system design ensure sterility and consistency.*
The Angel system is a clinically advanced, research-backed platform for delivering personalized, evidence-based regenerative treatments, including skin rejuvenation, scar therapy, hair restoration, and wound healing.1-5 It is widely used in regenerative medicine, orthopedics, and aesthetic dermatology, supported by extensive clinical research and validation.6
*Calculations based on the Angel Calculator. This tool allows you to input the desired volume and platelet/leukocyte concentrations in advance, then provides a recommendation for the appropriate hematocrit setting and the amount of blood that needs to be drawn from the patient.
How It Works
1. Blood Collection
A small-to-medium blood sample (40-180 mL) is drawn from the patient.
2. Automated Processing
The Angel system separates and concentrates PRP with adjustable PRP settings in a fully automated process, with no manual intervention required.
3. Application
The PRP is ready for injection into the treatment area.
Key Benefits
For Your Practice
Streamlined workflow integration through automated, programmable processing
Customizable PRP output with adjustable platelet and leukocyte concentrations
Reliable, reproducible results backed by scientific validation
For Your Patients
Clinically validated outcomes offer a safe alternative to synthetic injectables7
Supports natural skin regeneration, improving texture, tone, and elasticity
Minimally invasive and autologous using the patient’s own blood
Ready to Use the Angel PRP System in Your Practice?
Why Choose Arthrex Aesthetics?
We invite you to learn more about Arthrex and the positive contributions we are making to medicine and the communities we serve.
INNOVATIVE
Cutting-edge regenerative technology, developed with precision.
EFFICIENT
User-friendly system with minimal processing time.
SAFE
Closed-loop automation ensures sterility and consistency.
SUPPORTIVE
Training, resources, and ongoing physician education.
Educational Resources
Looking to educate your patients? Click here to request customized patient education materials, including videos and waiting room animations tailored to the Angel system.
Application Areas
The Angel system has a wide range of applications in aesthetic medicine, including skin rejuvenation, scar treatment, wound healing, alopecia treatment, and more.1, 3, 8-12
Innovative Treatments to Transform Your Practice
Innovative Treatments to Transform Your Practice
Skin Rejuvenation
Enhance skin quality by activating cell growth and the skin’s extracellular matrix.
Read More
Hair Restoration
Prepare customized PRP formulations with the Angel system to treat hair loss naturally.
Read More
Scar Reduction
Stimulate collagen production with highly concentrated PRP to treat surgical, trauma, or acne scars.
Read More
Skin Rejuvenation
Enhance skin quality by activating cell growth and the skin’s extracellular matrix.
Read More
Hair Restoration
Prepare customized PRP formulations with the Angel system to treat hair loss naturally.
Read More
Scar Reduction
Stimulate collagen production with highly concentrated PRP to treat surgical, trauma, or acne scars.
Read More
Stay ahead with expert-led training
Upcoming Events
At Arthrex Aesthetics, our commitment goes beyond products. We empower you through hands-on education, expert-led workshops, and scientific exchange so you can deliver the best outcomes with confidence.
Explore upcoming opportunities to learn more about the Angel system, and see all events to stay ahead in aesthetic medicine.
Hands-On Workshop and 3 Lectures
Live demonstration
on
November 28, 2025
in
Munich
.
Hands-On Workshop and 3 Lectures
Live demonstration
on
November 28, 2025
in
Munich
.
IMCAS World Congress 2026
Congress
on
January 29, 2026
in
Palais des Congres de Paris | Paris, France
.
IMCAS World Congress 2026
Congress
on
January 29, 2026
in
Palais des Congres de Paris | Paris, France
.
Ready to integrate the Angel PRP system into your practice?
Please fill out the form below and one of our experts will contact you for a personalized consultation. The fields marked with * are mandatory.
1
Autologous platelet-rich plasma (PRP) for treating androgenetic alopecia: A novel treatment protocol standardized on 2 cases
Maletic A, Dumic-Cule I, Brlek P, Zic R, Primorac D
-
University North
10.3390/jcm11247327
10.3390/jcm11247327
10
Exosomes isolated from platelet-rich plasma and mesenchymal stem cells promote recovery of function after muscle injury
Iyer SR, Scheiber AL, Yarowsky P, Henn RF, 3rd, Otsuru S, Lovering RM
-
Am J Sports Med
48(9):2277-2286
48(9):2277-2286
11
Clinical applications of exosomes in cosmetic dermatology
12
Platelet-rich plasma-derived extracellular vesicles: A superior alternative in regenerative medicine?
2
Characterizing RAPID platelet and leukocyte-rich plasma gels – an autologous, point-of-care medicine for diabetic foot ulcer treatment
Olszewska A, Pitchford S, Rickard J, Forbes B
-
King's College London
10.5920/bjpharm.1178
10.5920/bjpharm.1178
3
The addition of tissue stromal vascular fraction to platelet-rich plasma supplemented lipofilling does not improve facial skin quality: A prospective randomized clinical trial
van Dongen J, Boxtel J, Willemsen J, Brouwer L, Vermeulen K, Tuin A, Harmsen M, van der Lei B, Stevens H
-
Velthuis Clinic Rotterdam
10.1093/asj/sjab109
10.1093/asj/sjab109
4
Evaluation of not-activated and activated PRP in hair loss treatment: Role of growth factor and cytokine concentrations obtained by different collection systems
Gentile P, Cole JP, Cole MA, Garcovich S, Bielli A, Scioli MG, Orlandi A, Insalaco C, Cervelli V
-
University of Rome Tor Vergata
10.3390/ijms18020408
10.3390/ijms18020408
5
Successful treatment of corticosteroid-resistant ophiasis-type alopecia areata (AA) with platelet-rich plasma (PRP)
6
Illustrated Guide to Collagen Induction with Platelet-Rich Plasma (PRP).
7
The efficiency and safety of platelet-rich plasma dressing in the treatment of chronic wounds: A systematic review and meta-analysis of randomized controlled trials
8
Therapeutic potential of extracellular vesicles (exosomes) derived from platelet-rich plasma: a literature review
9
Exosomes derived from platelet-rich plasma promote the re-epithelization of chronic cutaneous wounds via activation of YAP in a diabetic rat model