Angel® PRP System

Customized PRP Concentration at the Touch of a Button

Angel PRP System with advanced closed-loop automation delivering highly concentrated platelet-rich plasma for aesthetic treatments

What Is the Angel System?

The Angel system is a customizable platelet-rich plasma (PRP) preparation system that supports the increasing demand for regenerative therapies in aesthetic medicine. It enables the sterile, automated separation of whole blood into tailored PRP formulations, with adjustable platelet and leukocyte concentrations to meet individual treatment needs.

With the ability to process up to 180 mL of blood and deliver platelet concentrations up to 18× over baseline, the Angel system also allows for precise control over leukocyte levels—including leukocyte-poor PRP for sensitive applications and leukocyte-rich PRP for enhanced regenerative effects. Its neutrophil-low PRP setting helps minimize inflammation, while the proprietary 3-sensor technology and closed system design ensure sterility and consistency.*

The Angel system is a clinically advanced, research-backed platform for delivering personalized, evidence-based regenerative treatments, including skin rejuvenation, scar therapy, hair restoration, and wound healing.1-5 It is widely used in regenerative medicine, orthopedics, and aesthetic dermatology, supported by extensive clinical research and validation.6

*Calculations based on the Angel Calculator. This tool allows you to input the desired volume and platelet/leukocyte concentrations in advance, then provides a recommendation for the appropriate hematocrit setting and the amount of blood that needs to be drawn from the patient.

How It Works

1. Blood Collection

A small-to-medium blood sample (40-180 mL) is drawn from the patient.

2. Automated Processing

The Angel system separates and concentrates PRP with adjustable PRP settings in a fully automated process, with no manual intervention required.

3. Application

The PRP is ready for injection into the treatment area.

Key Benefits

For Your Practice

Streamlined workflow integration through automated, programmable processing

Customizable PRP output with adjustable platelet and leukocyte concentrations

Reliable, reproducible results backed by scientific validation

For Your Patients

Clinically validated outcomes offer a safe alternative to synthetic injectables7

Supports natural skin regeneration, improving texture, tone, and elasticity

Minimally invasive and autologous using the patient’s own blood

Ready to Use the Angel PRP System in Your Practice?

Safety and Effectiveness

Scientific Validation and Clinical Evidence

Explore the scientific foundation behind PRP and its applications in aesthetic medicine.

PRP Proven Effective in Regenerative Medicine, Orthopedics, and Aesthetic Dermatology
Reference:
Illustrated Guide to Collagen Induction with Platelet-Rich Plasma (PRP): Rejuvenation Face, Neck, Décolleté, Hands.
KVM - Der Medizinverlag
–‍
Kolster B, Paasch U. Quintessence Publishing;
–‍ Source:
2019.
2019.
Autologous PRP Effective for Androgenetic Alopecia
Reference:
Autologous platelet-rich plasma (PRP) for treating androgenetic alopecia: A novel treatment protocol standardized on 2 cases
University North
–‍
Maletic A, Dumic-Cule I, Brlek P, Zic R, Primorac D
–‍ Source:
10.3390/jcm11247327
10.3390/jcm11247327
Angel PRP System Increases Hair Density
Reference:
Evaluation of not-activated and activated PRP in hair loss treatment: Role of growth factor and cytokine concentrations obtained by different collection systems
University of Rome Tor Vergata
–‍
Gentile P, Cole JP, Cole MA, Garcovich S, Bielli A, Scioli MG, Orlandi A, Insalaco C, Cervelli V
–‍ Source:
10.3390/ijms18020408
10.3390/ijms18020408
Effective Alopecia Areata Treatment Without Pharmaceuticals
Reference:
Successful treatment of corticosteroid-resistant ophiasis-type alopecia areata (AA) with platelet-rich plasma (PRP)
Women's College Hospital
–‍
Donovan J
–‍ Source:
10.1016/j.jdcr.2015.07.004
10.1016/j.jdcr.2015.07.004
PRP Supports Healing in Diabetic Foot Ulcers
Reference:
Characterizing RAPID platelet and leukocyte-rich plasma gels – an autologous, point-of-care medicine for diabetic foot ulcer treatment
King's College London
–‍
Olszewska A, Pitchford S, Rickard J, Forbes B
–‍ Source:
10.5920/bjpharm.1178
10.5920/bjpharm.1178
PRP With Lipofilling Improves Patient Satisfaction With Facial Appearance
Reference:
The addition of tissue stromal vascular fraction to platelet-rich plasma supplemented lipofilling does not improve facial skin quality: A prospective randomized clinical trial
Velthuis Clinic Rotterdam
–‍
van Dongen J, Boxtel J, Willemsen J, Brouwer L, Vermeulen K, Tuin A, Harmsen M, van der Lei B, Stevens H
–‍ Source:
10.1093/asj/sjab109
10.1093/asj/sjab109
PRP Dressings Proven Safe and Effective for Chronic Wounds
Reference:
The efficiency and safety of platelet-rich plasma dressing in the treatment of chronic wounds: A systematic review and meta-analysis of randomized controlled trials
J Pers Med
–‍
Li S, Xing F, Yan T, Zhang S, Chen F
–‍ Source:
10.3390/jpm13030430
10.3390/jpm13030430

Why Choose Arthrex Aesthetics?

We invite you to learn more about Arthrex and the positive contributions we are making to medicine and
the communities we serve.

INNOVATIVE


Cutting-edge regenerative technology, developed with precision.

EFFICIENT

User-friendly system with minimal processing time.

SAFE

Closed-loop automation ensures sterility and consistency.

SUPPORTIVE

Training, resources, and ongoing physician education.

Educational Resources

Looking to educate your patients? Click here to request customized patient education materials, including videos and waiting room animations tailored to the Angel system.

Application Areas

The Angel system has a wide range of applications in aesthetic medicine, including skin rejuvenation, scar treatment, wound healing, alopecia treatment, and more.1, 3, 8-12

Innovative Treatments to Transform Your Practice
Innovative Treatments to Transform Your Practice

Skin Rejuvenation

Hair Restoration

Scar Reduction

Person lying on a treatment bed while a gloved professional applies a device to the forehead and holds a syringe labeled ACP for wrinkle treatment with PRP.Patient receiving PRP injections for receding hairline to promote hair restoration and treat androgenetic alopecia in an aesthetic clinic.Medical professional injecting a syringe into a patient’s knee for scar treatment with PRP while wearing white gloves.
Stay ahead with expert-led training

Upcoming Events

At Arthrex Aesthetics, our commitment goes beyond products. We empower you through hands-on education, expert-led workshops, and scientific exchange so you can deliver the best outcomes with confidence.

Explore upcoming opportunities to learn more about the Angel system, and see all events to stay ahead in aesthetic medicine.

FAQs

How does the Angel system customize PRP formulations for individual patients?

How long is the spin time for the Angel system?

What is the platelet concentration of the Angel system?

How many times can the Angel processing kit be used?

Ready to integrate the Angel PRP system into your practice?

Please fill out the form below and one of our experts will contact you for a personalized consultation. The fields marked with * are mandatory.

1
Autologous platelet-rich plasma (PRP) for treating androgenetic alopecia: A novel treatment protocol standardized on 2 cases
Maletic A, Dumic-Cule I, Brlek P, Zic R, Primorac D
-
University North
10.3390/jcm11247327
10.3390/jcm11247327
2
Characterizing RAPID platelet and leukocyte-rich plasma gels – an autologous, point-of-care medicine for diabetic foot ulcer treatment
Olszewska A, Pitchford S, Rickard J, Forbes B
-
King's College London
10.5920/bjpharm.1178
10.5920/bjpharm.1178
3
The addition of tissue stromal vascular fraction to platelet-rich plasma supplemented lipofilling does not improve facial skin quality: A prospective randomized clinical trial
van Dongen J, Boxtel J, Willemsen J, Brouwer L, Vermeulen K, Tuin A, Harmsen M, van der Lei B, Stevens H
-
Velthuis Clinic Rotterdam
10.1093/asj/sjab109
10.1093/asj/sjab109
4
Evaluation of not-activated and activated PRP in hair loss treatment: Role of growth factor and cytokine concentrations obtained by different collection systems
Gentile P, Cole JP, Cole MA, Garcovich S, Bielli A, Scioli MG, Orlandi A, Insalaco C, Cervelli V
-
University of Rome Tor Vergata
10.3390/ijms18020408
10.3390/ijms18020408
5
Successful treatment of corticosteroid-resistant ophiasis-type alopecia areata (AA) with platelet-rich plasma (PRP)
Donovan J
-
Women's College Hospital
10.1016/j.jdcr.2015.07.004
10.1016/j.jdcr.2015.07.004
6
Illustrated Guide to Collagen Induction with Platelet-Rich Plasma (PRP): Rejuvenation Face, Neck, Décolleté, Hands.
Kolster B, Paasch U. Quintessence Publishing;
-
KVM - Der Medizinverlag
2019.
2019.
7
The efficiency and safety of platelet-rich plasma dressing in the treatment of chronic wounds: A systematic review and meta-analysis of randomized controlled trials
Li S, Xing F, Yan T, Zhang S, Chen F
-
J Pers Med
10.3390/jpm13030430
10.3390/jpm13030430